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and is the cause of the majority of HIV infections globally.The lower infectivity of HIV-2 as compared with HIV-1 implies that fewer people exposed to HIV-2 will be infected per exposure.If a woman is untreated, two years of breastfeeding results in an HIV/AIDS risk in her baby of about 17%. Due to the increased risk of death without breastfeeding in many areas in the developing world, the World Health Organization recommends either: (1) the mother and baby being treated with antiretroviral medication while breastfeeding being continued (2) the provision of safe formula.Lentiviruses share many morphological and biological characteristics.Many species of mammals are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period.Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses.Because of its relatively poor capacity for transmission, HIV-2 is largely confined to West Africa.

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Approximately 492,000 sexually active gay and bisexual men are at high risk for HIV; however, we have more tools to prevent HIV than ever before.The risk of acquiring HIV from a needle stick from an HIV-infected person is estimated as 0.3% (about 1 in 333) per act and the risk following mucous membrane exposure to infected blood as 0.09% (about 1 in 1000) per act.Preventive treatment involves the mother taking antiretrovirals during pregnancy and delivery, an elective caesarean section, avoiding breastfeeding, and administering antiretroviral drugs to the newborn.The mechanism of CD4 T cell depletion, although apoptosis may also be a factor.