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She began her career as a child actress, starring in various television shows.
She rose to prominence in 2002 playing a shy school girl called Nina Tucker in the Australian soap opera Neighbours.
In an exclusive interview with The Australian Women's Weekly, Goodrem revealed that, since 2002, she had suffered from a head-to-toe rash, fatigue, weight loss, night sweats, and a lump on her neck.
This made Goodrem the first and only artist to have five number-one singles from a debut album.
Innocent Eyes is the best-selling album of the 2000s decade in Australia and the debut album with the most number-one singles.
The piano-based ballad "Born to Try", co-written by Audius Mtawarira, premiered on the show and reached number one on the ARIA Singles Chart and number three in the UK.
Born to Try was certified triple Platinum in Australia for sales of over 210,000 copies.In September 2004, she became the face of soft drink company Pepsi in Australia, appearing on the product, billboards, TV advertisements and performing an exclusive show for competition winners.Goodrem's second album Mistaken Identity, was released in Australia on 8 November 2004 and debuted at number one on the ARIA Albums chart.The album's third single "Innocent Eyes" again reached number one on the ARIA Singles Chart and number nine in the UK.