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Clinical data Multiple trials, all published by the same authors, suggest a role for policosanol in intermittent claudication and platelet aggregation inhibition. In a 10-week, randomized, comparative study, policosanol 10 mg/day was increased the initial and absolute claudication distances in patients with intermittent claudication. In another 20-week, randomized, double-blind comparative study, policosanol 10 mg twice daily was associated with improvements in initial and absolute claudication distances. Ticlopidine 250 mg twice daily was the comparator drug that exhibited similar improvements with no differences between treatment groups. Trials published in 2006 in the United States, Germany, Netherlands, Canada, and South Africa found no effect on blood lipid profiles at dosages of 10 to 80 mg daily over 4 to 12 weeks. Additionally, no synergy with atorvastatin was demonstrated in one of these trials. Octacosanol ingestion and its effects on metabolic responses to submaximal cycle ergometry, reaction time and chest and grip strength . Jim Jordan, who used to coach wrestling at Ohio State University, was interviewed by a law firm investigating allegations that a now-dead team doctor sexually abused male athletes there decades ago, his spokesman confirmed Wednesday.

The White House struggled on Wednesday to contain a political outcry and confusion over U. President Donald Trump's summit with Russian President Vladimir Putin, denying Trump ever meant to say that Moscow was no longer targeting the United States. CAUGHT ON CAMERA: Police say a bicyclist who weaved past the gates blocking access to a bridge over a river in eastern Wisconsin escaped serious injury after falling into the gap that was created when the bridge started to rise.Ted Williams is the last major league baseball player to hit over .400. WATCH: More than 100 survivors who went public with gut-wrenching stories of abuse by former USA Gymnastics doctor Larry Nassar joined in a show of solidarity on Wednesday as they accepted an award for courage at the annual ESPYs ceremony.The Boston Red Sox slugger captivated millions with his dazzling swing and towering homers throughout the 1940s and 1950s in competition with New York Yankees hero Joe Di Maggio. CAUGHT ON CAMERA: Police say a bicyclist who weaved past the gates blocking access to a bridge over a river in eastern Wisconsin escaped serious injury after falling into the gap that was created when the bridge started to rise.Ted Williams is the last major league baseball player to hit over .400.

The Boston Red Sox slugger captivated millions with his dazzling swing and towering homers throughout the 1940s and 1950s in competition with New York Yankees hero Joe Di Maggio.Animal and human studies have demonstrated few adverse reactions from policosanol. Limited animal and human studies have found policosanol to be safe. Clinical data Despite the proliferation of studies primarily conducted by researchers in Cuba in the late 1990s and early 2000 proclaiming the efficacy of policosanol in lowering cholesterol, more recent studies have failed to validate early expectations.