Moc 6415a updating your
What that finding might mean is unknown at present.Myocardial blush grades, STR, and clinical events also were not different, but the TROFI trial was not designed or powered for those secondary outcomes. (5) of the previous meta-analysis have now updated their work with several important additions.In an elegant meta-analysis published 5 years ago, Bavry et al.(1) reported that aspiration thrombectomy prior to percutaneous coronary intervention (PCI) in acute ST segment–elevation myocardial infarction (STEMI) can be beneficial.We and others have shown that total ischemic time is the correct focus of attention for reperfusion in STEMI (6,7).To further illustrate its importance, we used the ischemic time and infarct size data reported in the present meta-analysis (Fig. Based on data from studies in animals and humans, it appears that a total ischemic time of Ischemic Time Versus Infarct Size The x-axis shows mean ischemic time in hours.
A simple regression line is shown; the data points are nonadjusted and nonweighted.It could be something as simple as a run away script or learning how to better use E-utilities, for more efficient work such that your work does not impact the ability of other researchers to also use our site.To restore access and understand how to better interact with our site to avoid this in the future, please have your system administrator contact [email protected] mechanical thrombectomy nor embolic protection devices were found to provide similar benefits or any benefit at all in the meta-analysis.
Subsequently, the American College of Cardiology/American Heart Association (ACC/AHA) STEMI guidelines endorsed the use of aspiration thrombectomy with PCI in STEMI, with a Class IIa (Level of Evidence: B) recommendation (2).
Using data from 30 studies of 6,415 patients, they found improvements in 2 surrogate markers of coronary flow and reperfusion, with more Thrombolysis In Myocardial Infarction (TIMI) blush grade of 3 at the conclusion of the procedure, and more ST-segment resolution (STR) in the group with aspiration thrombectomy compared with PCI without thrombectomy.