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If you can write Perl, the module Net:: Open SSH:: Parallel allows to write scripts that perform actions in parallel on remote hosts via SSH quite easyly.
It contains a sample script for changing passwords that you can use as a base.
I don't know about "best", and whether it's possible for all of the non-Linux *nix machines in your mix, but have you looked at puppet or cfengine for this kind of activity?
You will already have a file for your standard backups, so you need to create another one called something like dsm_db2which contains the following.